Synthetic Biology as a Strategic Asset

by Bo Layer, CTO | June 9, 2025

Synthetic Biology as a Strategic Asset

The ability to engineer biological systems is opening up a new and powerful frontier in national security. This article provides an overview of the state-of-the-art in synthetic biology and its profound implications, from creating novel, self-healing materials and biofuels to developing advanced biosensors that can detect chemical or biological agents with unprecedented sensitivity. I also discuss the critical importance of establishing ethical frameworks and robust biosecurity protocols for this powerful new domain.

For most of human history, we have been at the mercy of biology. We have been shaped by it, limited by it, and often killed by it. But that is beginning to change. We are now entering an era where we can engineer biology, where we can design and build new biological systems from the ground up. This is the field of synthetic biology, and it is poised to have a more profound impact on our world than any technology that has come before it. And that includes the world of national security.

The potential applications of synthetic biology for defense are staggering. Imagine a uniform that can detect the presence of a chemical or biological agent and automatically decontaminate itself. Imagine a self-healing material that can repair a hole in a fuel tank or a crack in an aircraft wing. Imagine a network of microscopic biosensors that can be scattered across a city to provide early warning of a pandemic or a bioterrorism attack. These are not science fiction; they are the kinds of capabilities that synthetic biology will make possible in the very near future.

But with great power comes great responsibility. The same technology that can be used to create life-saving medicines and materials can also be used to create devastating new weapons. A synthetically engineered virus could be far more deadly than anything that has ever occurred in nature. This is a threat that we must take with the utmost seriousness.

That is why the development of robust biosecurity protocols and ethical frameworks must go hand-in-hand with the science. We need to have a national, and indeed international, conversation about the rules of the road for this powerful new technology. We need to invest in the technologies that can detect and counter the misuse of synthetic biology. And we need to ensure that this research is done in a transparent and responsible manner.

At ROE Defense, we are committed to exploring the potential of synthetic biology to enhance our national security, but we are also committed to doing so in a way that is safe, secure, and ethical. This is a technology with the power to change the world. It's up to us to ensure that it changes it for the better.